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Test Code LAB9496 Activated, Senescent and Exhausted T Cell Panel

Performing Section

Immunology/Flow

Purpose/Principle

Characterization of activated, senescent, and exhausted T cells by flow cytometry.

Special Collection Notes

No Gel

Specimen Type

Whole Blood:
Purple Top -EDTA

Specimen Volume

Preferred: 3.0 mL
Minimum: 0.5 mL

Processing Instructions

Submit whole blood -DO NOT CENTRIFUGE.
Store and send ambient.
Sample must received into the lab Monday-Friday(before noon). Do not send sample on Friday (after noon), Saturday, Sunday or holidays.

Temperature

Ambient

Test Components

CD4+ CD38-/HLADR+
CD4+CD38+/HLADR-
CD4+ CD38+/HLADR+
CD4+CD57+
CD4+PD-1+
CD8+CD38-/HLADR+
CD8+CD38+/HLADR-
CD8+CD38+/HLADR+
CD8+CD57+
CD8+PD-1+

Reference Range

CD4+ CD38-/HLADR+

0 up to 5 years: 0-4% of CD4 + T Cells

5 years and up : 0-22% of CD4 + T Cells

 

CD4+CD38+/HLADR-

0 up to 5 years: 76-97% of CD4 + T Cells

5 years and up : 14-66% of CD4 + T Cells

 

CD4+CD38-/HLADR+

0 up to 5 years: 1-5% of CD4 + T Cells

5 years and up: 0-6% of CD4 + T Cells

 

CD4+CD57+

0 up to 5 years: 0-17% of CD4 + T Cells

5 years and up : 0-41% of CD4 + T Cells

 

CD4+PD-1+

0 up to 5 years: 28-49% of CD4 + T Cells

5 years and up: 24-67% of CD4 + T Cells

 

CD8+CD38-/HLADR+

0 up to 5 years: 0-3% of CD8 + T Cells

5 years and up: 0-37% of CD8 + T Cells

 

CD8+CD38+/HLADR-

0 up to 5 years: 62-100% of CD8 + T Cells

5 years and up: 8-51% of CD8 + T Cells

 

CD8+CD38+/HLADR+

0 up to 5 years: 0-9% of CD8 + T Cells

5 years and up: 0-25% of CD8 + T Cells

 

CD8+CD57+

0 up to 5 years: 0-24% of CD8 + T Cells

5 years and up: 0-64% of CD8 + T Cells

 

CD8+PD-1+

0 up to 5 years: 6-18% of CD8 + T Cells

5 years and up: 0-63% of CD8 + T Cells

TAT

48 Hours

Sample Stability

Ambient: 24 hours

Additional Notes

Testing must be performed within 24 hours.

 

Specimen will be rejected if clotted.

Aliases

ASET
ASET T Cells
Activated and Exhausted T Cells

CPT

88184
88185 X 7

Test/Batch Schedule

Monday-Friday Noon

Method

Flow Cytometry