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HelpTest Code LAB9283 EZH2 Gene Analysis
Performing Section
PRECISION DIAGNOSTICS
Purpose/Principle
CHCO Oncology Single Gene Sequence Analysis utilizes next-generation sequencing technology to detect somatic variants in the requested single gene. The assay evaluates the coding regions and adjacent intronic bases of the specified gene for DNA variants. The assay is designed to detect SNV and small indel events with >99% accuracy down to a 5% minor allelic frequency. Paired tumor normal testing is not available for somatic single gene requests.
Special Collection Notes
Collect specimen according to standard operating procedure.
Specimen Type
Whole Blood/Bone Marrow : Purple Top Tube-EDTAMouth: Buccal Swab
Tissue (Fresh-Frozen, Paraffin Embedded, or RPMI)
Specimen Volume
Whole Blood/Bone Marrow
Preferred: 4.0 mL
Minimum: 0.5 mL
*Receipt of blood or bone marrow within 72 hours of collection. Delays may impact nucleic acid quality.
Tissue
Preferred: uncut paraffin-embedded tissue block. Slides: 1 stained and 10 unstained - 10 micron thick slides
*Receipt within 24 hours of cutting or as soon as possible. Delays may impact nucleic acid quality.
Processing Instructions
Store and ship ambient. If transport is longer than 4 hours send refrigerated on cold pack.
For frozen tissue please send on dry ice- ASAP.
Temperature
Ambient/Refrigerated
Test Components
EZH2
Reference Range
ResultNo clinically significant variants identified
Variant(s)
This component has no reference ranges
TAT
21 days
Additional Notes
If targeted known variant testing is desired please order TARGETED KNOWN VARIANTS FAMILIAL ANALYSIS [LAB8635]Aliases
Oncology Single Gene Analysis Next Generation Sequencing (NGS)
CPT
81479