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Test Code LAB9077 Somatic Overgrowth Vascular Anomalies DNA Analysis

Aliases

Germline testing
Somatic testing

Performing Section

PRECISION DIAGNOSTICS

Specimen Type

Whole Blood/Purple Top Tube (K2 EDTA) or Buccal Swab. Tissue (Fresh Frozen, Paraffin Embedded (FFPE) or RPMI)

Specimen Volume

  • Optimal Volume: 4.0 ml
  • Minimum Volume: 0.5 ml

Processing Instructions

Receipt within 24 hours of cutting or as soon as possible. Delays may impact nucleic acid quality.

TAT

21 days

CPT

81479

Special Collection Notes

Collect specimen according to standard operating procedure

Additional Notes

Paired tumor normal analysis available for somatic specimens

Method

Next Generation Sequencing

Purpose/Principle

This panel includes DNA analysis of 67 genes that have been described in the diagnosis for Somatic Overgrowth Vascular Anomalies.

ACVRL1, AKT1, AKT2, AKT3, ARAF, BRAF, CCBE1, CCM2, CCND2, CCND3, CDKN1C, CTNNB1, DIS3L2, DNMT3A, EED, ELMO2, ENG, EPHB4, EZH2, FGFR1, FLT4, FOXC2, GATA2, GJC2, GLMN, GNA11, GNA14, GNAQ, GNAS, GPC3, HRAS, IDH1, IDH2, KIF11, KRAS, KRIT1, MAP2K1, MAP3K3, MET, MTOR, MYC, NRAS, PDCD10, PDGFRB, PHF6, PIGA, PIK3CA, PIK3R1, PIK3R2, PTCH1, PTEN, PTPN14, PTPRD, RASA1, RNF125, RNF135, SETD2, SMAD4, SMO, SOX18, STAMBP, SUZ12, TEK, TINF2, TSC1, TSC2, VEGFC