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HelpTest Code LAB9077 Comprehensive Somatic Overgrowth Vascular Anomalies DNA Analysis
Performing Section
PRECISION DIAGNOSTICS
Purpose/Principle
This panel includes DNA analysis of 67 genes that have been described in the diagnosis for Somatic Overgrowth Vascular Anomalies?.
Special Collection Notes
Collect specimen according to standard operating procedure.
Specimen Type
Whole Blood/Bone Marrow : Purple Top Tube-EDTAMouth: Buccal Swab
Tissue (Fresh-Frozen, Paraffin Embedded, or RPMI)
Specimen Volume
Whole Blood/Bone Marrow
Preferred: 4.0 mL
Minimum: 0.5 mL
*Receipt of blood or bone marrow within 72 hours of collection. Delays may impact nucleic acid quality.
Tissue
Preferred: uncut paraffin-embedded tissue block. Slides: 1 stained and 10 unstained - 10 micron thick slides
*Receipt within 24 hours of cutting or as soon as possible. Delays may impact nucleic acid quality.
Processing Instructions
Store and ship ambient. If transport is longer than 4 hours send refrigerated on cold pack.
For frozen tissue please send on dry ice- ASAP.
Temperature
Ambient/Refrigerated
Test Components
Gene content:
ACVRL1, AKT1, AKT2, AKT3, ARAF, BRAF, CCBE1, CCM2, CCND2, CCND3, CDKN1C, CTNNB1, DIS3L2, DNMT3A, EED, ELMO2, ENG, EPHB4, EZH2, FGFR1, FLT4, FOXC2, GATA2, GJC2, GLMN, GNA11, GNA14, GNAQ, GNAS, GPC3, HRAS, IDH1, IDH2, KIF11, KRAS, KRIT1, MAP2K1, MAP3K3, MET, MTOR, MYC, NRAS, PDCD10, PDGFRB, PHF6, PIGA, PIK3CA, PIK3R1, PIK3R2, PTCH1, PTEN, PTPN14, PTPRD, RASA1, RNF125, RNF135, SETD2, SMAD4, SMO, SOX18, STAMBP, SUZ12, TEK, TINF2, TSC1, TSC2, VEGFC
Reference Range
ResultNo clinically significant variants identified
Paired Normal Specimen
This component has no reference ranges
Variant(s)
This component has no reference ranges
TAT
21 days
Aliases
Somatic Overgrowth and Vascular Anomalies DNA Analysis
SOVA, Comprehensive
CPT
81479