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Test Code LAB8582 FLT3 Gene Analysis

Performing Section

PRECISION DIAGNOSTICS

Purpose/Principle

CHCO Oncology Single Gene Sequence Analysis utilizes next-generation sequencing technology to detect somatic variants in the requested single gene. The assay evaluates the coding regions and adjacent intronic bases of the specified gene for DNA variants. The assay is designed to detect SNV and small indel events with >99% accuracy down to a 5% minor allelic frequency. Paired tumor normal testing is not available for somatic single gene requests.

Special Collection Notes

Collect specimen according to standard operating procedure.

Specimen Type

Whole Blood/Bone Marrow : Purple Top Tube-EDTA

 

Mouth: Buccal Swab

 

Tissue (Fresh-Frozen, Paraffin Embedded, or RPMI)

Specimen Volume

Whole Blood/Bone Marrow

Preferred: 4.0 mL

Minimum: 0.5 mL

*Receipt of blood or bone marrow within 72 hours of collection. Delays may impact nucleic acid quality.

 

Tissue

Preferred: uncut paraffin-embedded tissue block. Slides: 1 stained and 10 unstained - 10 micron thick slides

*Receipt within 24 hours of cutting or as soon as possible. Delays may impact nucleic acid quality.

Processing Instructions

Store and ship ambient. If transport is longer than 4 hours send refrigerated on cold pack.
For frozen tissue please send on dry ice- ASAP.

Temperature

Ambient/Refrigerated

Test Components

FLT3

Reference Range

Result

No clinically significant variants identified

 

Variant(s)

This component has no reference ranges

TAT

21 days

Additional Notes

If targeted known variant testing is desired please order TARGETED KNOWN VARIANTS FAMILIAL ANALYSIS [LAB8635]

Aliases

Oncology Single Gene Analysis Next Generation Sequencing (NGS)

CPT

81245
81246