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Test Code LAB8532 ALPS Syndrome

Performing Section

Immunology/Flow

Purpose/Principle

Flow cytometry analysis of CD3+CD4-CD8-TCRab+ (Double Negative T Cells or DNTs) that are characteristic of Autoimmune Lymphoproliferative Syndrome (ALPS).

Special Collection Notes

No Gel

Specimen Type

Whole Blood:
Purple Top -EDTA (Preferred)
Dark Green Top -Sodium Heparin

Specimen Volume

Preferred: 1.0 mL
Minimum: 0.2 mL

Processing Instructions

Submit whole blood -DO NOT CENTRIFUGE.
Store and send ambient.
Sample must received into the lab Monday-Friday(before noon). Do not send sample on Friday (after noon), Saturday, Sunday or holidays.

Temperature

Ambient

Test Components

TCRAB DNT

Reference Range

<2.5%

TAT

48 Hours

Sample Stability

Ambient: 48 hours

Additional Notes

Specimen will be rejected if clotted.

Aliases

ALPS
Autoimmune Lymphoproliferative Syndrome Panel
Canale-Smith syndrome
DNT (Double Negative T Cells)

CPT

88184
88185 × 5

Test/Batch Schedule

Monday-Friday Noon

Method

Flow Cytometry