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Test Code LAB7518 Myeloid Panel (DNA Analysis)

Performing Section

PRECISION DIAGNOSTICS

Purpose/Principle

This panel includes DNA analysis 50 genes with clinical significance for the diagnosis, prognosis, and therapeutic decision making for myeloid neoplasms.

Special Collection Notes

Collect specimen according to standard operating procedure.

Specimen Type

Whole Blood/Bone Marrow : Purple Top Tube-EDTA

 

Mouth: Buccal Swab

 

Tissue (Fresh-Frozen, Paraffin Embedded, or RPMI)

Specimen Volume

Whole Blood/Bone Marrow

Preferred: 4.0 mL

Minimum: 0.5 mL

*Receipt of blood or bone marrow within 72 hours of collection. Delays may impact nucleic acid quality.

 

Tissue

Preferred: uncut paraffin-embedded tissue block. Slides: 1 stained and 10 unstained - 10 micron thick slides

*Receipt within 24 hours of cutting or as soon as possible. Delays may impact nucleic acid quality.

Processing Instructions

Store and ship ambient. If transport is longer than 4 hours send refrigerated on cold pack.
For frozen tissue please send on dry ice- ASAP.

Temperature

Ambient/Refrigerated

Test Components

Gene content:
ASXL1, BCOR, BCORL1, BRAF, CALR, CBL, CEBPA, CSF3R, CXCR4, DDX41, DNMT3A, ETV6, EZH2, FLT3, GATA1, GATA2, HRAS, IDH1, IDH2, JAK1, JAK2, JAK3, KDM6A, KIT, KMT2A, KRAS, MPL, MYD88, NF1, NOTCH1, NPM1, NRAS, PHF6, PPM1D, PTEN, PTPN11, RAD21, RUNX1, SETBP1, SF3B1, SH2B3, SRSF2, STAG2, STAT3, TET2, TP53, U2AF1, WT1, ZRSR2

Reference Range

Result

No clinically significant variants identified

 

TMB, Classification

Baseline

 

TMB, Mutation Rate

This component has no reference ranges

 

TMB, Total Number of Variants

This component has no reference ranges

 

Myeloid Variant(s)

This component has no reference ranges

TAT

21 days

Aliases

Hematological Neoplasms NGS Panel

CPT

81450