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HelpTest Code LAB7485 B Cell Gene Rearrangement Analysis, MRD
Purpose/Principle
To identify and track clonal B cell immunoglobulin heavy chain (IGH) gene rearrangements using Next-Generation Sequencing (NGS)
Performing Section
PRECISION DIAGNOSTICS
Specimen Type
Whole Blood or Bone Marrow/Purple Top Tube (K2 EDTA). Tissue (Fresh Frozen, Paraffin Embedded (FFPE) or RPMI)
Specimen Volume
Optimal Volume: 4.0 ml Minimum Volume: 0.5 ml Formalin-fixed, paraffin-embedded tissue block preferred or 10 micron unstained slides. (10 count).
Special Collection Notes
Collect specimen according to standard operating procedure
TAT
10 days
Method
Next Generation Sequencing
Additional Notes
Reportable range: ≥0.01% clonal frequency
CPT
81261