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HelpTest Code LAB7177 HVA and VMA with Creatinine, Urine
Aliases
Homovanillic Acid and Vanillylmandelic Acid
3-Methoxy-4-Hydroxymandelic Acid
Specimen Type
Urine:
Sterile Container
Processing Instructions
Client:
Store and ship sample frozen on dry ice.
Specimen Volume
Preferred: 4.0 mL
Minimum: 1.5 mL
Temperature
Frozen (dry ice)
Sample Stability
Frozen at -20 Celsius: 30 days
Frozen at -80 Celsius: Indefinitely
Additional Notes
Creatinine performed in chemistry.
Test/Batch Schedule
Mon and Thur
TAT
5 days
Test Components
Homovanillic Acid, Urine
Vanillylmandelic Acid, Urine
Reference Range
Homovanillic Acid0 up to 3 Months: 0.0-32.0 mg/g UCr
3 Months up to 1 Years: 0.0-36.4 mg/g UCr
1 Years up to 2 Years: 0.0-27.9 mg/g UCr
2 Years up to 5 Years: 0.0-21.7 mg/g UCr
5 Years up to 10 Years: 0.0-15.7 mg/g UCr
10 Years up to 13 Years: 0.0-9.7 mg/g UCr
13 Years up to 16 Years: 0.0-7.5 mg/g UCr
16 Years up to Unspecified: 0.0-7.7 mg/g UCr
Vanillylmandelic Acid
0 up to 3 Months: 0.0-19.8 mg/g UCr
3 Months up to 1 Years: 0.0-22.5 mg/g UCr
1 Years up to 2 Years: 0.0-18.8 mg/g UCr
2 Years up to 5 Years: 0.0-12.7 mg/g UCr
5 Years up to 10 Years: 0.0-11.2 mg/g UCr
10 Years up to 13 Years: 0.0-8.6 mg/g UCr
13 Years up to 16 Years: 0.0-6.9 mg/g UCr
16 Years up to Unspecified: 0.0-4.8 mg/g UCr
CPT
83150
84585
Performing Section
Biochemical Genetics
Purpose/Principle
This method measures the amount of HVA and VMA present using stable isotope dilution methodology. HVA and VMA and the isotopically labeled HVA and VMA internal standard are solvent extracted from acidified urine and their trimethylsilyl (TMS) derivatives are separated by gas chromatography and identified by mass spectrometry.