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Test Code LAB7177 HVA and VMA with Creatinine, Urine

Aliases

Homovanillic Acid and Vanillylmandelic Acid
3-Methoxy-4-Hydroxymandelic Acid

Performing Section

Biochemical Genetics

Purpose/Principle

This method measures the amount of HVA and VMA present using stable isotope dilution methodology. HVA and VMA and the isotopically labeled HVA and VMA internal standard are solvent extracted from acidified urine and their trimethylsilyl (TMS) derivatives are separated by gas chromatography and identified by mass spectrometry.

Specimen Type

Urine:
Sterile Container

Specimen Volume

Preferred: 4.0 mL
Minimum: 1.5 mL

Processing Instructions

Client:
Store and ship sample frozen on dry ice.

Temperature

Frozen (dry ice)

TAT

5 days

Test Components

Homovanillic Acid, Urine
Vanillylmandelic Acid, Urine

CPT

83150
84585

Sample Stability

Frozen at -20 Celsius: 30 days
Frozen at -80 Celsius: Indefinitely

Additional Notes

Creatinine performed in chemistry.

Test/Batch Schedule

Mon and Thur

Reference Range

Homovanillic Acid

0 up to 3 Months: 0.0-32.0 mg/g UCr

3 Months up to 1 Years: 0.0-36.4 mg/g UCr

1 Years up to 2 Years: 0.0-27.9 mg/g UCr

2 Years up to 5 Years: 0.0-21.7 mg/g UCr

5 Years up to 10 Years: 0.0-15.7 mg/g UCr

10 Years up to 13 Years: 0.0-9.7 mg/g UCr

13 Years up to 16 Years: 0.0-7.5 mg/g UCr

16 Years up to Unspecified: 0.0-7.7 mg/g UCr

 

Vanillylmandelic Acid

0 up to 3 Months: 0.0-19.8 mg/g UCr

3 Months up to 1 Years: 0.0-22.5 mg/g UCr

1 Years up to 2 Years: 0.0-18.8 mg/g UCr

2 Years up to 5 Years: 0.0-12.7 mg/g UCr

5 Years up to 10 Years: 0.0-11.2 mg/g UCr

10 Years up to 13 Years: 0.0-8.6 mg/g UCr

13 Years up to 16 Years: 0.0-6.9 mg/g UCr

16 Years up to Unspecified: 0.0-4.8 mg/g UCr