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Test Code LAB6760 Benzoic Acid

Performing Section

Biochemical Genetics

Purpose/Principle

Benzoate is used as a glycine scavenging medication in the treatment of nonketotic hyperglycinemia and inborn errors of metabolism characterized by hyperammonemia. This method measures the amount of benzoate in serum or plasma using stable isotope dilution methodology

Specimen Type

Serum or Plasma:
Green Top -Lithium Heparin (Preferred)
Dark Green Top – Sodium Heparin
Red Top -Plain
Gold Top -SST

Specimen Volume

Preferred: 3.0 mL (1 mL serum/plasma)
Minimum: 1.5 mL (0.5 mL serum/plasma)

Processing Instructions

CENTRIFUGE per procedure
Pipette off plasma or serum into pour off tube
Attach original tube to pour off tube with rubber band
Store and ship sample frozen on dry ice

Temperature

Frozen (dry ice)

Test Components

Benzoic Acid

Reference Range

≤ 2.50 nmol/L

TAT

7 days

Sample Stability

Frozen @-20 Celsius: 30 days
Frozen @ -80 Celsius: Indefinitely

Aliases

Benzoate

CPT

82542

Test/Batch Schedule

Run once a week (day varies)