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HelpTest Code LAB6750 Methylmalonic Acid
Performing Section
Biochemical Genetics
Purpose/Principle
Methylmalonic acidemias are characterized by the accumulation and excretion of methylmalonic acid. This method measures the amount of methylmalonic acid present using stable isotope dilution methodology.
Specimen Type
Serum or Plasma:
Green Top -Lithium Heparin (Preferred)
Dark Green Top – Sodium Heparin
Red Top -Plain
Gold Top -SST
Specimen Volume
Preferred: 1.5 mL
Minimum: 0.5 mL
Processing Instructions
Green or Gold top-CENTRIFUGE per procedure / Red Top – Clot 60 minutes in upright position
Pipette off plasma or serum into pour off tube
Attach original tube to pour off tube with rubber band
Store and ship sample Frozen on dry ice.
Temperature
Frozen (dry ice)
Test Components
Methylmalonic Acid
Reference Range
0.0-0.8 mcmol/L
TAT
7 days
Sample Stability
Refrigerated: 24 hours
Frozen @-20 Celsius: 30 days
Frozen @ -80 Celsius: Indefinitely
Aliases
MMA
CPT
83921
Test/Batch Schedule
Tue and Thur