Test Code LAB6498 Chimerism Analysis, Post-Transplant

Aliases

Chimerism Study -Post Sample
Bone Marrow Transplant Engraftment by STR

Performing Section

PRECISION DIAGNOSTICS

Purpose/Principle

This method uses the Promega PowerPlex® Fusion System for analysis.
Numerous sequence variations have been defined in the human genome which can be used to specifically characterize and distinguish individuals and to define their relatedness within a family or a specific population.

Special Collection Notes

Collect specimen according to standard operating procedure.

Specimen Type

Whole Blood/Bone Marrow : Purple Top Tube-EDTA

Mouth: Buccal Swab

Tissue (Fresh-Frozen, Paraffin Embedded, or RPMI)

Specimen Volume

Whole Blood/Bone Marrow

Preferred: 4.0 mL

Minimum: 0.5 mL

*Receipt of blood or bone marrow within 72 hours of collection. Delays may impact nucleic acid quality.

Tissue

Preferred: uncut paraffin-embedded tissue block. Slides: 1 stained and 10 unstained - 10 micron thick slides

*Receipt within 24 hours of cutting or as soon as possible. Delays may impact nucleic acid quality.

Processing Instructions

Store and ship ambient. If transport is longer than 4 hours send refrigerated on cold pack.
For frozen tissue please send on dry ice- ASAP.

Temperature

Ambient/Refrigerated

TAT

4 days

Test Components

Chimerism Donor Percent
Chimerism Donor Result
Chimerism Recipient Percent
Chimerism Recipient Result

CPT

81267

Additional Notes

Specimen will be rejected if frozen or heparinized bone marrow or peripheral blood

Reference Range

Chimerism Donor Percent

0-100%

Chimerism Donor Result

Detected, Greater Than 95%

Chimerism Recipient Percent