Sign in →

Test Code LAB6218 Pyruvic Acid, Blood

Important Note

Please contact the Laboratory at 720-777-6711 for special kit PRIOR to
collection of this testing.
 

Additional Codes

PYR

Reporting Name

Pyruvic Acid, B

Useful For

Screening for possible disorders of mitochondrial metabolism, when used in conjunction with blood lactate collected at the same time, to determine the lactate-to-pyruvate ratio

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Whole blood


Additional Testing Requirements


This test does not calculate the lactate:pyruvate ratio. To obtain this information, both this test and LACS1 / Lactate, Plasma must be ordered. The ratio can be calculated from the results obtained from these tests. A separate specimen must be obtained for lactate testing, see LACS1 / Lactate, Plasma.



Specimen Required


Call 800-533-1710 or 507-266-5700 to order special collection tube.

 

Patient Preparation: Fasting (at least 4 hours)

Supplies: Perchloric Acid-Pyruvate Tube (T012)

Container/Tube: Special collection tube containing 2.5 mL of 6% perchloric acid

Specimen Volume: Exactly 1 mL

Collection Instructions:

1. Special collection tube must be prechilled prior to collection.

2. Draw enough blood directly into syringe to add exactly 1 mL of blood to the prechilled special collection tube.

3. Taking care to not spill any of the preservative, cautiously remove the cap from the tube.

4. Immediately transfer blood, once drawn, to the prechilled, special collection tube, recap, and shake vigorously to mix.

Additional Information:

1. Check expiration date before using. Supplied collection tube expires 14 months after preparation.

2. If perchloric acid (preservative) spills, obtain a new, prechilled tube.


Specimen Minimum Volume

See Specimen Required

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole blood Refrigerated 15 days PYRUVATE

Reference Values

0.08-0.16 mmol/L

 

NIH Unit

0.7-1.4 mg/dL

Day(s) Performed

Monday, Wednesday

CPT Code Information

84210

Report Available

2 to 5 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK

Method Name

Spectrophotometry (SP)

Genetics Test Information

The lactate:pyruvate (L:P) ratio is considered a helpful (not diagnostic) tool in the evaluation of patients with possible disorders of mitochondrial metabolism, especially in patients with neurologic dysfunction and either elevated or normal blood lactate levels. Pyruvic acid levels alone have little clinical utility.