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HelpTest Code LAB5984 Porphyrins, Quantitative, Random, Urine
Additional Codes
PQNRU
Reporting Name
Porphyrins, QN, Random, UUseful For
Preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda and during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria when specimen transport will not exceed 72 hours
Testing Algorithm
The following algorithms are available:
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Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineOrdering Guidance
This random urine test should be ordered when the specimen will reach Mayo Clinic Laboratories within 72 hours. If transportation will take longer than 72 hours, order PQNU / Porphyrins, Quantitative, 24 Hour, Urine and follow collection guidelines.
Shipping Instructions
Ship specimen in amber bottle to protect from light.
Necessary Information
Include a list of medications the patient is currently taking.
Specimen Required
Patient Preparation: Patient should not consume any alcohol for the 24 hours before specimen collection.
Supplies: Urine Container - Amber, 60 mL (T596)
Container/Tube: Amber, 60-mL urine container
Specimen Volume: 20 to 50 mL
Collection Instructions: Collect a random urine specimen.
Specimen Minimum Volume
15 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Frozen | 72 hours | LIGHT PROTECTED |
Special Instructions
Reference Values
Uroporphyrins, Octacarboxyl:
≤30 nmol/L
Heptacarboxylporphyrins:
≤7 nmol/L
Hexacarboxylporphyrins:
≤2 nmol/L
Pentacarboxyporphyrins:
≤5 nmol/L
Copropprphyrin, Tetracboxyl:
≤110 nmol/L
Porphobilinogen:
≤1.3 mcmol/L
Day(s) Performed
Monday through Friday
CPT Code Information
84110-Porphobilinogen, quantitative
84120-Porphyrins, quantitation and fractionation
Genetics Test Information
This test is preferred test during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria. The random urine collection for this test allows for the diagnosis to be established and treatment to be initiated quickly. However, this test should only be ordered when the specimen will be received at Mayo Clinic Laboratories within 72 hours of collection. If it will be longer, PQNU / Porphyrins, Quantitative, 24 Hour, Urine should be ordered and collection guidelines must be followed.
Testing includes porphobilinogen which is useful in the evaluation of the acute porphyrias.
This is the preferred test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda.
Report Available
2 to 4 daysReject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Method Name
High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection/Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.