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Test Code LAB10118 VERY-LONG CHAIN ACYL-COA DEHYDROGENASE (VLCAD) ACTIVITY USING LC-MSMS

Aliases

VLCAD
VLCAD Activity

Special Collection Notes

Mix well after collection

Specimen Type

Whole Blood:
Purple Top Tube-EDTA

Processing Instructions

DO NOT CENTRIFUGE. Store refrigerated and send on wet ice via courier OR ship overnighted on cold pack (See Resources for more shipping info).

Specimen Volume

Preferred: 3.0 mL
Minimum: 1.0 mL

Temperature

Refrigerated

Sample Stability

Refrigerated: 48 hours

Additional Notes

Any sample that is received frozen or ambient will be rejected.

Test/Batch Schedule

Run once a week on Thursday (day may vary)

TAT

Routine: 10 days
STAT: 72 hours

Test Components

VLCAD Activity

Reference Range

Normal VLCAD Activity Reference Range

1.35-2.95 nmol/min/mg protein

 

Carrier VLCAD Activity Reference Range

1.03-1.49 nmol/min/mg protein

 

Affected VLCAD Activity Reference Range

0.25-0.86 nmol/min/mg protein

CPT

0257U

Performing Section

Biochemical Genetics

Purpose/Principle

Clinical teams can use this test to help clarify whether a patient has VLCAD deficiency often as follow up to abnormal newborn screening results or inconclusive molecular genetic testing.