Sign in →

Test Code LAB10118 VERY-LONG CHAIN ACYL-COA DEHYDROGENASE (VLCAD) ACTIVITY USING LC-MSMS

Important Note

TESTING IS CURRENTLY DOWN FOR TROUBLESHOOTING. ANY SPECIMENS SUBMITTED WILL BE MAINTAINED IN GOOD CONDITION UNTIL TESTING RESUMES. AT THIS TIME, THERE IS NO ESTIMATED TIMEFRAME FOR WHEN THIS ASSAY WILL BE BACK ONLINE. WE APOLOGIZE FOR THE DELAY AND ANY INCONVENIENCE THIS MAY CAUSE. PLEASE CONTACT US WITH ANY QUESTIONS OR CONCERNS.

Aliases

VLCAD
VLCAD Activity

Purpose/Principle

Clinical teams can use this test to help clarify whether a patient has VLCAD deficiency often as follow up to abnormal newborn screening results or inconclusive molecular genetic testing.

Performing Section

Biochemical Genetics

Specimen Type

Whole Blood:
Purple Top Tube-EDTA

Specimen Volume

Preferred: 3.0 mL
Minimum: 1.0 mL

Special Collection Notes

Mix well after collection

Processing Instructions

DO NOT CENTRIFUGE. Store refrigerated and send on wet ice via courier OR ship overnighted on cold pack (See Resources for more shipping info).

Temperature

Refrigerated

Sample Stability

Refrigerated: 48 hours

TAT

Routine: 10 days
STAT: 72 hours

Test/Batch Schedule

Run once a week on Thursday (day may vary)

Test Components

VLCAD Activity

Reference Range

Normal VLCAD Activity Reference Range

1.35-2.95 nmol/min/mg protein

 

Carrier VLCAD Activity Reference Range

1.03-1.49 nmol/min/mg protein

 

Affected VLCAD Activity Reference Range

0.25-0.86 nmol/min/mg protein

Additional Notes

Any sample that is received frozen or ambient will be rejected.

CPT

0257U