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HelpTest Code FKEMS Ketamine and Metabolite Screen, Plasma
Specimen Required
***Must submit one specimen per order. Specimens cannot be shared between multiple orders.***
Specimen Type: Plasma
Collection Container/Tube: Lavender-top or pink top (EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions:
1. Draw blood in an EDTA (lavender top or pink top) tube(s). Plasma gel tube is not acceptable.
2. Centrifuge and send 3 mL of plasma refrigerated in a preservative-free plastic vial.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| FKETC | Ketamine and Metabolite Confirm, P | No | No |
Testing Algorithm
Confirmation test, Ketamine and Metabolite Confirmation (FKETC), will be performed, if appropriate, at an additional charge.
Method Name
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Ketamine and Metabolite Screen, PSpecimen Type
Plasma EDTASpecimen Minimum Volume
0.9 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma EDTA | Refrigerated (preferred) | 14 days |
| Frozen | 270 days | |
| Ambient | 14 days |
Reject Due To
| Other | Polymer gel separation tube (SST or PST) |
Reference Values
Reporting limit determined each analysis
Units: ng/mL
Norketamine: None Detected
The intravenous administration of 2 mg/kg of Ketamine followed by continuous infusion of 41 mcg/kg/minute produced an average steady-state plasma concentration of 2200 ng Ketamine/mL and an average peak Norketamine level of 1050 ng/mL which occurred near the end of the 3 hour infusion.
Ketamine: None Detected
Reported levels during anesthesia: 500-6500 ng/mL
Performing Laboratory
NMS LabsCPT Code Information
80307-Screen
80357-Confirmation, if appropriate
Day(s) Performed
Monday through Sunday