Reference Values

Reference Range: <2.50 index

Interpretive Criteria:

<2.50: Negative

≥2.50: Positive

This assay detects Filaria IgG4 associated with infections caused by the major filarial parasites, including Dirofilaria immitis, Wuchereria brancrofti, Brugia malayi, and Onchocerca volvulus.

Chronic filarial infections manifesting as elephantiasis may not show a significant IgG4 response and cannot be ruled out using this test. Samples containing antibodies to other nematodes, particularly Strongyloides, may cross-react in the assay.