Specimen Required

Collection Container: Plastic urine container

Specimen Volume: 5-25 mL

Collection Instructions:

1. Collect 5-25 mL random urine without preservative.
2. Ship frozen in a plastic container.

NOTE: Submit with specimen:

1. Clinical history/Preliminary diagnosis

-Because URSO can mask detection of bile acid synthetic defects it is preferable for patients to be off Urso or Actigall for 5 days before sample collection.

-If possible, send Urine & Serum (ZW166 - Bile Acids Serum, referral lab code 9001004). Urine is analyzed for all patients - if Urine shows evidence of a metabolic abnormality, Serum will be tested. Urine and serum must be ordered separately as they are 2 separate tests with separate charges.