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HelpTest Code DIS Human Leukocyte Antigens (HLA) Class I and II Disease Association Typing, Low Resolution, Blood
Ordering Guidance
This test should be ordered if both human leukocyte antigen (HLA) class I and class II results are wanted for disease association.
If only needing patient's HLA class I typing for disease association, order 1DIS / Human Leukocyte Antigens (HLA)-A-B-C Disease Association Typing Low Resolution, Blood.
If only needing patient's HLA class II typing for disease association, order 2DIS / Human Leukocyte Antigens (HLA)-DR-DQ Disease Association Typing Low Resolution, Blood.
Specimen Required
Container/Tube: Yellow top (ACD solution A or B)
Specimen Volume: 6 mL
Collection Instructions: Send whole blood in original tube. Do not aliquot.
Additional Information: Specimen acceptability is based on extracted DNA concentration and not sample age.
Useful For
Identifying class I and II human leukocyte antigens (HLA) for potential disease associations or markers for drug hypersensitivity
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| 1DIS | HLA-A-B-C DisAssoc Typing LowRes,B | Yes | Yes |
| 2DIS | HLA-DR-DQ DisAssoc Typing LowRes,B | Yes | Yes |
Method Name
Polymerase Chain Reaction (PCR)/Next-Generation Sequencing (NGS)
Reporting Name
HLA CI-CII DisAssoc Typing LowRes,BSpecimen Type
Whole Blood ACDSpecimen Minimum Volume
3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood ACD | Ambient (preferred) | |
| Refrigerated | ||
Reject Due To
| Extracted DNA | Reject |
Reference Values
Not applicable
Day(s) Performed
Monday, Wednesday
Report Available
7 to 17 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
81370
81376 x3